Prostaglandin F<sub>2?</sub>-<wbr/>1-<wbr/>glyceryl ester-<wbr/>d<sub>5</sub>

Prostaglandin F2?–1-glyceryl ester-d5

CAT N°: 13883
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From 92.00 78.20

Prostaglandin F2?-1-glyceryl ester-d5 (PGF2?-1-glyceryl ester-d5) contains five deuterium atoms. It is intended for use as an internal standard for the quantification of PGF2?-1-glyceryl ester by GC- or LC-MS. 2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the central cannabinoid receptor.{4614,5306} Incubation of 2-AG with cyclooxygenase 2 and specific PGH2 isomerases in cell cultures and isolated enzyme preparations results in PG glyceryl ester formation.{11045} The biosynthesis of PGH, PGD, PGE, PGF, and thromboxane A-2-glyceryl ester compounds have all been documented. The 2-glyceryl ester moiety equilibrates rapidly (within minutes) with the more stable 1-glyceryl ester, producing a 10:90 2:1-glyceryl ester mixture in typical aqueous media. While the stability and metabolism of PGF2?-1-glyceryl ester has been investigated, little is known about its intrinsic biological activity.{10555}

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