Prostaglandin E<sub>2</sub>-d<sub>9</sub>

Prostaglandin E2-d9

CAT N°: 10581
Price:

From 106.00 90.10

Prostaglandin E2-d9 (PGE2-d9) is intended for use as an internal standard for the quantification of PGE2 (Item No. 14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.{1585,1558,437,1330} The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.{1422} Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 9-oxo-11?,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
  • Correlated keywords
    • PGE2 metabolites EP1 EP2 EP3 EP4 prostaglandins pharma:2 deuterateds deuteriums LC-MS LC/MS GC-MS GC/MS mass spectrometry MS standards
  • Product Overview:
    Prostaglandin E2-d9 (PGE2-d9) is intended for use as an internal standard for the quantification of PGE2 (Item No. 14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation.{1585,1558,437,1330} The effects of PGE2 are transduced by at least four distinct receptors designated EP1, EP2, EP3, and EP4.{1422} Affinity constants (Kd) of PGE2 for these receptors range from 1-10 nM depending on the receptor subtype and tissue.

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