Propoxur

Propoxur

CAT N°: 25628
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48.00 40.80

Propoxur is a carbamate insecticide and an inhibitor of acetylcholinesterase.{38711} It is lethal to German cockroaches (B. germanica) with LD50 values of 2.45, 4.73, and 1.06 ?g per insect for newly emerged males, newly emerged females, and 4-week-old nymphs, respectively. Propoxur induces lactate dehydrogenase (LDH) release from and inhibits the growth of flounder gill cells (IC50s = 86.59 and 89.96 ?g/ml, respectively) via induction of necrosis.{39951} It also induces yolk sac and pericardial edema in zebrafish embryos when used at concentrations of 100 and 200 ?g/ml. Propoxur (8.3 mg/kg) inhibits rat blood and brain cholinesterase, decreases ambulation and rearing in an open field test, and increases latency to escape foot shock after an audio stimulus in the two-way active avoidance box in rats.{39952}

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