Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) Peptide
Amyloid-? (1-8, A2V) is a truncated form of amyloid-? (A?) that contains a valine to alanine substitution at position 2...
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Prolactin releasing peptide (PrRP) is a 31-amino acid neuropeptide involved in regulating food intake.{43061} It is found in the hypothalamus, medulla, and pituitary in rats.{43062} PrRP is an agonist of the G-protein coupled receptors GPR10/hGR3 and neuropeptide FF receptor (hNPFF2; Kis = 1 and 19 nM, respectively).{43062,43063} It stimulates calcium mobilization in HEK293 cells expressing GPR10 (EC50 = 1.5 nM) and radiolabeled GTP?S binding to membrane homogenates from CHO cells transfected with hNPFF2 (EC50 = 240 nM).{43062,43063} PrRP (100 nM) increases the release of gonadotropin-releasing hormone (GnRH; Item No. 24762), vasoactive intestinal peptide (VIP; Item No. 24996), and galanin (Item No. 24456) from rat medial basal hypothalamic explants.{43064} It increases plasma levels of luteinizing hormone, follicle stimulating hormone, and testosterone in male rats when administered at an intracerebroventricular dose of 5 nmol.{43064} PrRP reduces food intake in fasted rats to 58.4, 53.4, and 55.4% of control levels when administered at doses of 1, 5, and 10 nmol, respectively.{43061}
Territorial Availability: Available through Bertin Technologies only in France
| Size | 500 µg |
|---|---|
| Shipping | dry ice |
| CAS number | 215510-22-8 |
| Molecular formula | C160H252N56O42S |
| Smiles | NC([C@@H](NC([C@H](CCCNC(N)=N)NC(CNC([C@H](C(C)C)NC([C@@H]1CCCN1C([C@H](CCCNC(N)=N)NC([C@@]([C@H](CC)C)([H])NC(CNC([C@H](CCCNC(N)=N)NC([C@H](CO)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]2CCCN2C([C@H](CC(N)=O)NC([C@@]([C@H](CC)C)([H])NC([C@@H](NC([C@@H]3CCCN3C([C@@]([C@@H](C)O)([H])NC([C@H](CCCNC(N)=N)NC([C@@]([C@H](CC)C)([H])NC([C@H](CCC(O)=O)NC([C@@H](NC([C@H](CO)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCNC(N)=N)NC([C@H](CO)N[H])=O)=O)=O)CC4=CN=CN4)=O)=O)CC5=CN=CN5)=O)=O)CCSC)=O)=O)=O)=O)=O)=O)CC(O)=O)=O)=O)=O)=O)C)=O)CC6=CNC7=C6C=CC=C7)=O)CC8=CC=C(O)C=C8)=O)C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC9=CC=CC=C9)=O |
| Molecular weight | 3664,2 |
| Formulation | A lyophilized powder |
| Purity | ≥95% |
| Custom code | 3504.00 |
| UNSPSC code | 12352100 |
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