SBC-110736

SBC-110736

CAT N°: 23103
Price:

From 55.00 46.75

SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).{53726} It increases LDL receptor (LDLR) levels in HepG2 cells expressing PCSK9 when used at a concentration of 400 nM. SBC-110736 (8 mg/kg per day) reduces plasma total cholesterol levels by a mean of 38% in mice fed a high-fat diet. It also reduces plasma LDL cholesterol levels in mice fed a high-fat diet and exhibits an additive effect when administered in combination with atorvastatin (Item No. 10493).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-acetamide
  • Correlated keywords
    • SBC110736 PCSK-9 Hep-G2 HepG-2
  • Product Overview:
    SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).{53726} It increases LDL receptor (LDLR) levels in HepG2 cells expressing PCSK9 when used at a concentration of 400 nM. SBC-110736 (8 mg/kg per day) reduces plasma total cholesterol levels by a mean of 38% in mice fed a high-fat diet. It also reduces plasma LDL cholesterol levels in mice fed a high-fat diet and exhibits an additive effect when administered in combination with atorvastatin (Item No. 10493).

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