(±)-4-hydroxy Propranolol ?-D-Glucuronide

Biochemicals - Receptor Pharmacology

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Cat No: 22383

Biochemicals - Receptor Pharmacology

(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol (Item No. 18630), which is a metabolite of propranolol.{36036,36037} The apparent half-life of (±)-4-hydroxy propranolol β-D-glucuronide is similar to propranolol a...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1-naphthalenyl ?-D-glucopyranosiduronic acid

Correlated keywords:

119445-21-5 HOPG HO-P-G b-D-glucuronide hydroxypropranolol b-adrenergic b1 b2 b3 t1/2

Product Overview:
(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol (Item No. 18630), which is a metabolite of propranolol.{36036,36037} The apparent half-life of (±)-4-hydroxy propranolol β-D-glucuronide is similar to propranolol and 4-hydroxy propranolol.{36037} Propranolol is a β-adrenergic antagonist, and the active enantiomer, (S)-(-)-propranolol (Item No. 17291), has log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.{25151,25396}

Size	500 µg
Shipping	dry ice
CAS Number	94731-13-2
Molecular Formula	C₂₂H₂₉NO₉
SMILES	OC(CNC(C)C)COC1=CC=C(O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2)C3=C1C=CC=C3
Molecular Weight	451,5
Formulation	A solid
Purity	≥90%
Custom Code	2918.99
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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