all-<em>trans</em>-5,6-epoxy Retinoic Acid

all-trans-5,6-epoxy Retinoic Acid

CAT N°: 22124
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all-trans-5,6-epoxy Retinoic acid (5,6-epoxy RA) is an agonist of all isoforms of the retinoic acid receptor (RAR; EC50s = 77, 35, and 4 nM for RAR?, RAR?, and RAR?, respectively).{34779} 5,6-epoxy RA (1 µM) also induces growth arrest of MCF-7 and NB4 cells in vitro.{34780, 34781} It is a natural metabolite of all-trans retinoic acid (Item No. 11017), which is a metabolite of vitamin A.{34778}

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