SW155246

SW155246

CAT N°: 21865
Price:

From 59.00 50.15

SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 ?M).{42214} It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 ?M). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 ?M). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 ?M.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide
  • Correlated keywords
    • SW-155246 DNMT-1 3 A-549
  • Product Overview:
    SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1; IC50 = 1.2 ?M).{42214} It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 ?M). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 ?M). It also inhibits genomic methylation in HeLa cells when used at concentrations ranging from 10 to 18.6 ?M.

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