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MHC Class I Monoclonal Antibody (Clone W6/32)
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Cat No: 20898
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes.{33427} MHC class I molecules consist of two polypeptide...
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Territorial Availability: Available through Bertin Technologies only in France
Correlated keywords:
- P30443 P30460 P10321 HLAA HLAB HLAC P 30443 30460 10321 W632 W-632 6/32
Product Overview:
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes.{33427} MHC class I molecules consist of two polypeptide chains, an α or heavy chain, and β2-microglobulin, a non-covalently associated protein.{28687} Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules.{33425} Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove.{33426} HLA-class I MHC antigens are intrinsic membrane glycoproteins expressed on nucleated cells and non-covalently associated with an invariant β2-microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells and are thus important for antiviral and antitumor defense. {33425} Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules
Major histocompatibility complex (MHC) molecules, also designated human leukocyte antigen (HLA) molecules, are cell-surface receptors that bind foreign peptides and present them to T lymphocytes.{33427} MHC class I molecules consist of two polypeptide chains, an α or heavy chain, and β2-microglobulin, a non-covalently associated protein.{28687} Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules.{33425} Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove.{33426} HLA-class I MHC antigens are intrinsic membrane glycoproteins expressed on nucleated cells and non-covalently associated with an invariant β2-microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells and are thus important for antiviral and antitumor defense. {33425} Human HLA-class I antigens are represented by HLA-A, HLA-B, and HLA-C molecules
| Size | 100 µg |
| Shipping | dry ice |
| Host | Mouse |
| Antigen | Cell membranes of human tonsil lymphocytes |
| Clone | W6/32 |
| Isotype | IgG2 |
| Application(s) | FC and IP |
| Formulation | 100 µg of protein G purified IgG |
| Custom Code | 3822.19 |
| UNSPSC code | 12352203 |
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