Rutin (hydrate)

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Rutin (hydrate)

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Cat No: 19868

Biochemicals - Natural Products

Rutin is a flavonoid glycoside that has been found in buckwheat and has diverse biological activities.{30137,31793,16519,31794,31795} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals when used at a c...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-[[6-O-(6-deoxy-?-L-mannopyranosyl)-?-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one, trihydrate

Correlated keywords:

153-18-4 207671-50-9 auto-oxidation anti-cancer flavonol anti-oxidant anti-inflammatory Fe B 16 F 10

Product Overview:
Rutin is a flavonoid glycoside that has been found in buckwheat and has diverse biological activities.{30137,31793,16519,31794,31795} It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) and ABTS (Item No. 27317) radicals when used at a concentration of 163.79 µM, as well as inhibits iron autoxidation, in cell-free assays.{30137,31793} Dietary administration of rutin (0.2% w/v) reduces tumor growth and the number of lung metastases in a B16/F10 murine melanoma model.{16519} Rutin (50 and 100 mg/kg) decreases intestinal acidity, increases intestinal activity of superoxide dismutase (SOD) and catalase, and reduces intestinal levels of protein carbonyls and thiobarbituric acid reactive substances (TBARS) formation in a rat model of intestinal toxicity induced by methotrexate (Item No. 13960).{31794} It also increases the time spent exploring the novel object in the novel object recognition (NOR) test and increases recognition and discriminative indices in a rat model of short-term episodic memory deficits induced by scopolamine (Item No. 14108).{31795}

Size	25 g
Shipping	room temp.
CAS Number	250249-75-3
Molecular Formula	C₂₇H₃₀O₁₆ • 3H₂O
SMILES	O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(O)C(O)=C3)=C1O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)O4.O.O.O
Molecular Weight	664,6
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2907.29
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.