Ubiquinol

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Ubiquinol

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Cat No: 19677

Biochemicals - Ox Stress Reagents

Ubiquinol is a reduced form of coenzyme Q10 (CoQ10; Item No. 11506), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol).{63365} CoQ10 acts as an electron...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-[3,7,11,15,19,23,27,31,35,39-decamethyl-2E,6E,10E,14E,18E,22E,26E,30E,34E,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-1,4-benzenediol

Correlated keywords:

30291-37-3 CoQ10 CoQ-10 Co-Q10 semi-quinone ubisemi-quinone ubi-semiquinone FSP-1 dihydrocoenzyme Q10 kaneka QH ubidecarenol

Product Overview:
Ubiquinol is a reduced form of coenzyme Q10 (CoQ10; Item No. 11506), which exists in three redox states: fully oxidized (CoQ10/ubiquinone), partially reduced (semiquinone/ubisemiquinone), and fully reduced (ubiquinol).{63365} CoQ10 acts as an electron shuttle in the electron transport chain via its reduction to ubiquinol between mitochondrial complexes I and II, also known as NADH dehydrogenase and succinate dehydrogenase, respectively, and mitochondrial complex III, also known as cytochrome bc1 complex.{20670,63366} CoQ10 is also reduced to ubiquinol by ferroptosis suppressor protein 1 (FSP1) with NADPH as a cofactor, and ubiquinol traps lipid peroxyl radicals and inhibits lipid peroxidation helping to prevent ferroptosis.{50700}

Size	500 µg
Shipping	dry ice
CAS Number	992-78-9
Molecular Formula	C₅₉H₉₂O₄
SMILES	COC1=C(OC)C(O)=C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)\C)C(C)=C1O
Molecular Weight	865,4
Formulation	A crystalline solid
Purity	≥90%
Custom Code	2907.29
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.