VU0255035

VU0255035

CAT N°: 19353
Price:

From 237.00 201.45

VU0255035 is a competitive, orthosteric antagonist of the muscarinic M1 receptor (IC50 = 130 nM).{30840,30841} It displays at least 75-fold selectivity for M1 over other muscarinic receptors, as well as a panel of receptors, ion channels, and transporters.{30840,30841} VU0255035 is effective in cells and in vivo and brain penetrating, blocking pilocarpine-induced seizures without disrupting contextual fear conditioning in mice.{30840,30841} VU0255035 is used to examine the role of the M1 receptor in diverse situations.{25277,30842,30839}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[3-oxo-3-[4-(4-pyridinyl)-1-piperazinyl]propyl]-2,1,3-benzothiadiazole-4-sulfonamide
  • Correlated keywords
    • 1202864-36-5 VU255035 VU-255035 VU-0255035 orthosteric muscarinic M1 M-1 learning memory seizure CID24768606 CID-24768606 ML012
  • Product Overview:
    VU0255035 is a competitive, orthosteric antagonist of the muscarinic M1 receptor (IC50 = 130 nM).{30840,30841} It displays at least 75-fold selectivity for M1 over other muscarinic receptors, as well as a panel of receptors, ion channels, and transporters.{30840,30841} VU0255035 is effective in cells and in vivo and brain penetrating, blocking pilocarpine-induced seizures without disrupting contextual fear conditioning in mice.{30840,30841} VU0255035 is used to examine the role of the M1 receptor in diverse situations.{25277,30842,30839}

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