N<sup>1</sup>,N<sup>12</sup>-<wbr/>Diacetyl<wbr/>spermine (hydrochloride)

N1,N12–Diacetylspermine (hydrochloride)

CAT N°: 17918
Price:

From 102.00 86.70

N1,N12-Acetylspermine is a diacetylated derivative of spermine (Item No. 18041), an endogenous polyamine synthesized from spermidine (Item No. 14918), that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine.{29261} Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes.{27553,29231} Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.{28930}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N,N’-[1,4-butanediylbis(imino-3,1-propanediyl)]bis-acetamide, dihydrochloride
  • Correlated keywords
    • biomarker derivative spermine 61345-83-3
  • Product Overview:
    N1,N12-Acetylspermine is a diacetylated derivative of spermine (Item No. 18041), an endogenous polyamine synthesized from spermidine (Item No. 14918), that displays lower Km and higher Vmax values than spermine, making it a better substrate of polyamine oxidase than the non-acetylated polyamine.{29261} Spermine is required for eukaryotic cell growth and protein synthesis and is involved in the modulation of calcium-dependent immune processes.{27553,29231} Upregulation of N1,N12-acetylspermine has been linked to the incidence of cancer, making this natural polyamine a potential biomarker for cancer detection.{28930}

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