JWH 203 N-(4-hydroxypentyl) metabolite-d₅

Territorial Availability: Available through Bertin Technologies only in France

Technical Warning: Bertin Technologies restricts the sale of this product to licensed controlled substance laboratories and qualified academic research institutions. Please contact us for further details.

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• Synonyms
  • 2-(2-chlorophenyl)-1-(1-(4-hydroxypentyl)-1H-indol-3-yl-2,4,5,6,7-d5)ethan-1-one
• Correlated keywords
  • cannabinoids receptors JWHs 250 CB1 CB2 cannabimimetics forensics pains metabolites CBs JWH-250 JWH250 203 JWH203 JWH-203 metabolisms serum urine phase I hydroxylated hydroxypentyl neurosciences forensics analgesics chemicals phenylacetylindole agonists synthetics central peripheral 13634 phenylacetyl naphthoyl rings aminoalkylindoles potent binding binds activity physiological research applications LC-MS LC/MS GC-MS GC/MS mass spectrometry MS analytical references standards
• Product Overview:
  JWH 203 N-(4-hydroxypentyl) metabolite-d5 contains five deuterium atoms at the 2, 4 ,5, 6, and 7 positions. It is intended for use as an internal standard for the quantification of JWH 203 N-(4-hydroxypentyl) metabolite by GC- or LC-mass spectrometry. JWH 203 (Item No. 9000736) is an analgesic chemical from the phenylacetylindole family that acts as an agonist with Ki values of 8.0 and 7.0 nM at the central cannabinoid (CB1) and peripheral (CB2) receptors, respectively.{17655} Similar to the related 2′-methoxy compound JWH 250 (Item No. 13634), JWH 203 has a phenylacetyl group in place of the naphthoyl ring used in most aminoalkylindole cannabinoid compounds. Compared to JWH 250, JWH 203 displays slightly more potent binding affinities for the CB1 and CB2 receptors (JWH 250 Kis = 11 and 33 nM, respectively).{17655} JWH 203 N-(4-hydroxypentyl) metabolite is expected to be a metabolite of JWH 203 that would be detectable both in serum and in urine. While similar hydroxylated phase I metabolites of synthetic CBs retain activity, the physiological properties of this compound have yet to be determined.{20952,20953} This product is intended for research and forensic applications.