Q-Plex™ SARS-CoV-2 Human IgG (5-

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Q-Plex™ SARS-CoV-2 Human IgG (5-Plex)

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Cat No: 34964

Assay Kits - More Assay Kits

The Q-Plex™ SARS-CoV-2 Human IgG (5-Plex) array simultaneously recognizes human IgG antibodies to S1 and S2 subunits of the spike glycoprotein as well as antibodies specific for the nucleocapsid protein (NP). Whereas the spike glycoprotein is crucial ...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

721649 HU SARSCov2 SARSCov2S1 SARSCov2S2 glyco protein anti-viral covid-19 covid19 coronavirus corona virus serological

Product Overview:
The Q-Plex™ SARS-CoV-2 Human IgG (5-Plex) array simultaneously recognizes human IgG antibodies to S1 and S2 subunits of the spike glycoprotein as well as antibodies specific for the nucleocapsid protein (NP). Whereas the spike glycoprotein is crucial for the virus’ ability to attach to a cell, the NP is the primary protein that makes up the shell, or capsid, of the virus. The assay also detects antibodies towards the Fc region of sheep antibody to control for cross-reactivity between sample and the assay components. Finally, the kit uses detection of anti-human IgG as a positive control to ensure the assay performs to expectations. The multiplex assay allows for simultaneous indirect ELISA on the following five printed spots: SARS-CoV-2 Spike Glycoprotein (S1), a recombinant antigen which contains amino acids 1-674 of subunit 1. Spike S1 is expressed in mammalian HEK293 cells with a Sheep Fc-Tag. SARS-CoV-2 Spike Glycoprotein (S2) is a recombinant antigen which contains the Spike subunit 2 protein, amino acids 685-1211. Spike S2 is expressed in mammalian HEK293 cells with a Sheep Fc-Tag. SARS-CoV-2 Nucleocapsid (NP) is a recombinant antigen which contains amnio acids 1-419 of the viral nucleocapsid structural protein. NP is expressed in mammalian HEK293 cells. Sheep Fc, is a negative control to ensure no cross-reactivity occurs between human IgGs in the sample and the Fc-Tag on the SARS-Cov-2 Spike proteins. Anti-Human IgG is a positive control to ensure the kit performs and the IFU was followed correctly. Q-Plex™ plates are built by absorbing multiple distinct capture antibodies in a defined array to the bottom of each well. Our high-quality reagents help ensure the accuracy of your results. See Item No. 28264 to view pricing and specifications for the Q-View™ Imager LS. Species: Human Assay Type: Indirect Sample Type: Human Serum, Plasma, and Dried Whole Blood Assay Length: 2 hours Specificity: See Assay Validation Volume Required per Well: 2 µl Detection Method: Chemiluminescent Multiplex Format: 96-well solid plate [QuanSys Catalog No. 721649HU]

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Custom Code	3822.19
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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.