L-Glutamine-d5

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L-Glutamine-d₅

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Cat No: 34839

L-Glutamine-d5 is intended for use as an internal standard for the quantification of L-glutamine (Item No. 23716) by GC- or LC-MS. L-Glutamine is a non-essential amino acid involved in many biochemical processes. It is synthesized in vivo by glutamate...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

L-Glutamine-2,3,3,4,4-d5

Correlated keywords:

GCMS LCMS bio synthesis deuterium deuterated neuro transmitter NSC 27421 NSC27421 LGln

Product Overview:
L-Glutamine-d5 is intended for use as an internal standard for the quantification of L-glutamine (Item No. 23716) by GC- or LC-MS. L-Glutamine is a non-essential amino acid involved in many biochemical processes. It is synthesized in vivo by glutamate and ammonia.{41351} It serves as a substrate for glutamine synthetase in neurons for the biosynthesis of the major excitatory and inhibitory neurotransmitters glutamate and GABA.{41350} L-Glutamine decreases adhesion of sickle red blood cells (RBCs) to human umbilical vein endothelial cells (HUVECs) when incubated ex vivo with patient-derived autologous plasma either alone or with LPS.{41352} It has commonly been used in cell culture media. Formulations containing L-glutamine have been used in the treatment of sickle cell disease.

Size	1 mg
Shipping	dry ice
CAS Number	14341-78-7
Molecular Formula	C₅H₅D₅N₂O₃
SMILES	NC(C([2H])([2H])C([2H])([2H])[C@]([2H])(N)C(O)=O)=O
Molecular Weight	151,2
Formulation	A solid
Purity	≥99% deuterated forms (d1-d5)
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.