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CPPG

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    CPPG
  • CPPG
Cat No: 34362
Biochemicals - Receptor Pharmacology
Cayman

CPPG is an antagonist of group II and group III metabotropic glutamate receptors (mGluRs).{58662} It reverses inhibition of forskolin-induced cAMP accumulation induced by the mGluR group II selective agonist L-CCG-1 or the mGluR group III-selective ag...

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This product can only be bought through Cayman Chemical. Please contact us.

Territorial Availability: Available through Bertin Technologies only in France
Synonyms:
  • ?-amino-?-cyclopropyl-4-phosphono-benzeneacetic acid
Correlated keywords:
  • m GLUR LCCG1 LCCG-1 L-CCG1 LAP4
Product Overview:
CPPG is an antagonist of group II and group III metabotropic glutamate receptors (mGluRs).{58662} It reverses inhibition of forskolin-induced cAMP accumulation induced by the mGluR group II selective agonist L-CCG-1 or the mGluR group III-selective agonist L-AP4 (Item No. 14538) in rat cerebrocortical slices (IC50s = 46.2 and 2.2 nM, respectively). Intrathecal administration of CPPG reduces formalin-induced flinching in a rat model of inflammatory pain.{58663}
Size 1 mg
Shipping dry ice
CAS Number 183364-82-1
Molecular Formula C11H14NO5P
SMILES NC(C1=CC=C(P(O)(O)=O)C=C1)(C(O)=O)C2CC2
Molecular Weight 271,2
Formulation A solid
Purity ≥98%
Custom Code 2922.49
UNSPSC code 12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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