Roxatidine-d<sub>10</sub> (hemioxalate)

Roxatidine-d10 (hemioxalate)

CAT N°: 34007
Price:

From 276.00 234.60

Roxatidine-d10 is intended for use as an internal standard for the quantification of roxatidine by GC- or LC-MS. Roxatidine is a histamine H2 receptor antagonist and major active metabolite of roxatidine acetate (Item No. 21248).{62168} Roxatidine reduces histamine-induced adenylate cyclase production in guinea pig parietal cells (IC50 = 0.8 µM). It inhibits histamine-induced hydrogen ion accumulation in the same cells (pA2 = 7.03). Roxatidine (200 mg/kg) reduces small intestinal lesion area in a rat model of gastric mucosal injury induced by indomethacin (Item No. 70270).{62169}

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