Tectoridin

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Tectoridin

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Cat No: 33969

Biochemicals - Lipids

Tectoridin is a polyketide synthase-derived flavonoid glycoside and phytoestrogen that has been found in B. chinensis and has diverse biological activities.{54947,54943,54944,54945,54946} It scavenges hydroxyl radicals in a cell-free assay (IC50 = 178...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

7-(?-D-glucopyranosyloxy)-5-hydroxy-3-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one

Correlated keywords:

30142-53-1 Belamcanda shekanin GH 3 MCF7

Product Overview:
Tectoridin is a polyketide synthase-derived flavonoid glycoside and phytoestrogen that has been found in B. chinensis and has diverse biological activities.{54947,54943,54944,54945,54946} It scavenges hydroxyl radicals in a cell-free assay (IC50 = 178 µg/ml) and inhibits the formation of thiobarbituric acid reactive substances (TBARS) in egg yolk (IC50 = 86 µg/ml).{54943} Tectoridin (200 µM) activates thyroid hormone receptor- or estrogen receptor-mediated transcription in GH3 rat pituitary and MCF-7 human breast cancer cells, respectively, in reporter assays.{54944} It inhibits the production of prostaglandin E2 (PGE2; Item No. 14010) induced by thapsigargin (Item No. 10522) in isolated rat peritoneal macrophages when used at concentrations of 10 and 30 µM.{54945} Tectoridin (60 mg/kg) inhibits trabecular bone loss in a mouse model of osteoporosis induced by ovariectomy.{54946}

Size	5 mg
Shipping	dry ice
CAS Number	611-40-5
Molecular Formula	C₂₂H₂₂O₁₁
SMILES	O=C1C2=C(O)C(OC)=C(O[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)C=C2OC=C1C4=CC=C(C=C4)O
Molecular Weight	462,4
Formulation	A solid
Purity	≥98%
Custom Code	2938.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.