DTPA - C14H23N3O10 - Bertin Bioreagent

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DTPA

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Cat No: 33307

Biochemicals - More Biochemicals

DTPA is a cell-impermeable metal chelating agent.{64029,64030} It chelates copper, iron, zinc, and manganese, as well as calcium, magnesium, and plutonium.{64029,64031} DTPA has been used as a metal chelating agent in the study of ferroptosis.{35320} ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N,N-bis[2-[bis(carboxymethyl)amino]ethyl]-glycine

Correlated keywords:

6889-50-5 7575-40-8 13407-13-1 25737-54-6 49758-21-6 84932-15-0 573987-64-1 782415-12-7 803683-39-8 Chel 330 3PA PA SD PASD Clewat DA Complexon V D 1 D1 Dabeersen 503 Detapac Detarex DETP DETPA Dissolvine DPTA Hamp-Ex Monaquest CAI NSC7340 Titriplex Trilon CS

Product Overview:
DTPA is a cell-impermeable metal chelating agent.{64029,64030} It chelates copper, iron, zinc, and manganese, as well as calcium, magnesium, and plutonium.{64029,64031} DTPA has been used as a metal chelating agent in the study of ferroptosis.{35320} It reduces the skeletal plutonium burden and incidence of bone tumors, as well as increases survival in a mouse model of intravenous plutonium exposure when administered at a dose of 500 mg/kg.{64031} Formulations containing DTPA conjugated to radioactive compounds have been used as diagnostic agents for brain imaging, renal visualization, and lung imaging.

Size	25 g
Shipping	dry ice
CAS Number	67-43-6
Molecular Formula	C₁₄H₂₃N₃O₁₀
SMILES	O=C(CN(CCN(CCN(CC(O)=O)CC(O)=O)CC(O)=O)CC(O)=O)O
Molecular Weight	393,4
Formulation	A solid
Purity	≥95%
Custom Code	2922.49
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.