Tebuconazole-d9

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Tebuconazole-d₉

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Cat No: 33287

Biochemicals - Isotopically Labeled Standards

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole (Item No. 24052) by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi.{42004} It inhibits 14α-demethy...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

?-[2-(4-chlorophenyl)ethyl]-?-(1,1-dimethylethyl-d9)-1H-1,2,4-triazole-1-ethanol

Correlated keywords:

deuterated deuterium GCMS LCMS BAY HWG-1608 HWG1608 BAYHWG1608 BAYHWG Ustilago Sorghum MDAkb2 hydroxy-progesterone 17?hydroxyprogesterone CA 3-4 CA34

Product Overview:
Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole (Item No. 24052) by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi.{42004} It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively.{30331} It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay.{42005} Tebuconazole (50 and 100 mg/kg per day) administered during gestation reduces testosterone levels and increases testicular levels of progesterone and 17α-hydroxyprogesterone in male rat fetuses.{42006} It has a feminizing effect on male pups and a virilizing effect on female pups. When administered to rats gestationally through postnatal day 42, tebuconazole (20 and 60 mg/kg per day) leads to cell death of pyramidal cells in the CA3-4 region of the hippocampus and layer V of the cortex concomitant with impairment in learning the platform location in the Morris water maze.{42007}

Size	1 mg
Shipping	dry ice
CAS Number	1246818-83-6
Molecular Formula	C₁₆H₁₃ClD₉N₃O
SMILES	ClC(C=C1)=CC=C1CCC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])(O)CN2C=NC=N2
Molecular Weight	316,9
Formulation	A solid
Purity	≥99% deuterated forms (d1-d9)
Custom Code	3822.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.