Sophoricoside

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Sophoricoside

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Cat No: 31203

Biochemicals - Lipids

Sophoricoside is a polyketide synthase-derived isoflavone glycoside that has been found in S. japonica and has diverse biological activities.{60602,60599,60598,60600,60601} It inhibits lipid accumulation induced by oleic acid (Item Nos. 90260
24659)...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-[4-(?-D-glucopyranosyloxy)phenyl]-5,7-dihydroxy-4H-1-benzopyran-4-one

Correlated keywords:

100455-45-6 4?,5,7-Trihydroxyisoflavone 4?-?-D-glucopyranoside glucosyloxyisoflavone Spiraea Hep-G2

Product Overview:
Sophoricoside is a polyketide synthase-derived isoflavone glycoside that has been found in S. japonica and has diverse biological activities.{60602,60599,60598,60600,60601} It inhibits lipid accumulation induced by oleic acid (Item Nos. 90260
24659) in HepG2 cells and stimulates glucose uptake in C2C12 mouse skeletal muscle myoblasts when used at a concentration of 10 µM.{60599} Sophoricoside (2 mg/kg) reduces scratching behavior induced by compound 48/80 (Item No. 22173) or histamine (Item No. 33828) in mice, as well as reduces serum levels of IgE in a mouse model of atopic dermatitis.{60598} It increases serum levels of osteocalcin and alkaline phosphatase (ALP) and restores mechanical bone hardness in an ovariectomized rat model of osteoporosis.{60600} Sophoricoside (80 and 160 mg/kg) decreases hepatic cholesterol and triglyceride levels, serum LDL and apolipoprotein B levels, and hepatic injury in a mouse model of fructose-induced liver injury.{60601}

Size	50 mg
Shipping	dry ice
CAS Number	152-95-4
Molecular Formula	C₂₁H₂₀O₁₀
SMILES	OC1=CC(O)=C2C(OC=C(C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O4)C=C3)C2=O)=C1
Molecular Weight	432,4
Formulation	A solid
Purity	≥98%
Custom Code	2938.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.