Kaempferol 3-O-galactoside

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Cat No: 33747

Biochemicals - Natural Products

Kaempferol 3-O-galactoside is a flavonoid that has been found in C. vulgaris and has diverse biological activities, including anticancer, antioxidant, and anti-inflammatory properties.{60384,60385,60386} It inhibits secretory phospholipase A2 (sPLA2) ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

3-(?-D-galactopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Correlated keywords:

1401-67-8 11049-67-5 25103-16-6 38725-10-9 123049-37-6 178358-54-8 3-O-?-D-galactopyranoside Trifoliin glycoside Chlorella anti-cancer oxidant antiinflammatory NCIH460 H-460

Product Overview:
Kaempferol 3-O-galactoside is a flavonoid that has been found in C. vulgaris and has diverse biological activities, including anticancer, antioxidant, and anti-inflammatory properties.{60384,60385,60386} It inhibits secretory phospholipase A2 (sPLA2) with an IC50 value of 17.6 µM.{60384} Kaempferol 3-O-galactoside (12.5, 25, and 50 µM) decreases protein levels of Akt and induces apoptosis in NCI H460 non-small cell lung cancer (NSCLC) cells.{60385} It scavenges DPPH (Item No. 14805) radicals and superoxide anions in cell-free assays when used at a concentration of 200 µg/ml.{60386} Kaempferol 3-O-galactoside reduces ear and paw edema induced by phorbol 12-myristate 13-acetate (TPA; Item No. 10008014) and carrageenan, respectively, in mice when administered at a dose of 150 mg/kg.{60384}

Size	500 µg
Shipping	dry ice
CAS Number	23627-87-4
Molecular Formula	C₂₁H₂₀O₁₁
SMILES	O=C1C2=C(O)C=C(O)C=C2OC(C3=CC=C(C=C3)O)=C1O[C@@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO
Molecular Weight	448,4
Formulation	A solid
Purity	≥98%
Custom Code	2938.90
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.