Cysteamine-d4 (hydrochloride)

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Cysteamine-d₄ (hydrochloride)

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Cat No: 33297

Biochemicals - Isotopically Labeled Standards

Cysteamine-d4 is intended for use as an internal standard for the quantification of cysteamine (hydrochloride) (Item No. 22193) by GC- or LC-MS. Cysteamine is a stable aminothiol with radioprotective activities.{41003} It reduces ionizing radiation-i...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2-amino-ethanethiol-d4, monohydrochloride

Correlated keywords:

471248-04-1 deuterated deuterium GCMS LCMS CI-9148 CI9148 radio-protective

Product Overview:
Cysteamine-d4 is intended for use as an internal standard for the quantification of cysteamine (hydrochloride) (Item No. 22193) by GC- or LC-MS. Cysteamine is a stable aminothiol with radioprotective activities.{41003} It reduces ionizing radiation-induced death and chromosomal damage in mice in a dose-dependent manner.{41003,41004} Cysteamine binds rapidly and temporarily to plasma proteins upon administration and this activity is directly correlated to its radioprotective effects.{41004} In vitro, 0.1 mM cysteamine depletes 90% of free cystine from cystinotic fibroblasts.{41005} Formulations containing cysteamine have been used to treat nephropathic cystinosis and reduce glomerular deterioration in humans.

Size	1 mg
Shipping	dry ice
CAS Number	1219805-04-5
Molecular Formula	C₂H₃D₄NS • HCl
SMILES	NC([2H])([2H])C([2H])([2H])S.Cl
Molecular Weight	117,6
Formulation	A solid
Purity	≥99% deuterated forms (d1-d4)
Custom Code	3822.19
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.