3-Oxobetulin

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3-Oxobetulin

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Cat No: 33066

Biochemicals - Natural Products

3-Oxobetulin is a pentacyclic triterpenoid and derivative of betulinic acid (Item No. 11686) that has been found in I. macropoda and has diverse biological activities.{60301,60302,60303} It is active against the plant pathogenic fungi L. betulina and ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

28-hydroxy-lup-20(29)-en-3-one

Correlated keywords:

Oxo-betulin Betulonic alcohol tri-terpenoid penta-cyclic MT2 Hep-G2 Ilex Lenzites Laetiporus HIV1 semi-synthetic

Product Overview:
3-Oxobetulin is a pentacyclic triterpenoid and derivative of betulinic acid (Item No. 11686) that has been found in I. macropoda and has diverse biological activities.{60301,60302,60303} It is active against the plant pathogenic fungi L. betulina and L. sulphureus when used at a concentration of 30 µg/ml.{60302} 3-Oxobetulin reduces HIV-1 replication in MT-2 cells (IC50 = 4.1 µM) with a 50% cytotoxic concentration (CC50) value of greater than 100 µM.{60297} It inhibits cadmium-induced cytotoxicity in HepG2 cells in a concentration-dependent manner.{60303}

Size	1 mg
Shipping	dry ice
CAS Number	7020-34-0
Molecular Formula	C₃₀H₄₈O₂
SMILES	C[C@]1([C@]2([C@]([C@@]3([C@@](C(C)(C(CC3)=O)C)([H])CC2)C)([H])CC4)C)[C@@]4([H])[C@]([C@@H](CC5)C(C)=C)([H])[C@@]5(CO)CC1
Molecular Weight	440,7
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2906.19
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.