Succinylcholine (chloride hydrat

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Succinylcholine (chloride hydrate)

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Cat No: 32829

Biochemicals - Ion Channel Modulation

Succinylcholine is an agonist of muscle-type nicotinic acetylcholine receptors (nAChRs).{52931} It activates the muscle-type α1β1δε subunit-containing nAChR (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor) then induces desensitizati...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2,2?-[(1,4-dioxo-1,4-butanediyl)bis(oxy)]bis[N,N,N-trimethyl-ethanaminium, dichloride, dihydrate

Correlated keywords:

306-40-1306-40-1 ?3-?2 ?-3?2 ?3?-2 ?4 3?4 4 4?2 7 ? 1 ? ? African clawed frog xenopus

Product Overview:
Succinylcholine is an agonist of muscle-type nicotinic acetylcholine receptors (nAChRs).{52931} It activates the muscle-type α1β1δε subunit-containing nAChR (EC50 = 10.8 µM in X. laevis oocytes expressing the human receptor) then induces desensitization of the receptor. It is selective for the muscle-type nAChR over α3β2, α3β4, α4β2, or α7 subunit-containing neuronal nAChRs (IC50s = >100 µM). Succinylcholine (600 µg) induces neuromuscular block in isolated rat phrenic nerve-diaphragm preparations stimulated via the phrenic nerve.{52932} Formulations containing succinylcholine have been used as an adjunct to general anesthesia for its muscle relaxant properties.

Size	5 g
Shipping	dry ice
CAS Number	6101-15-1
Molecular Formula	C₁₄H₃₀N₂O₄ • 2Cl [2H₂O]
SMILES	O=C(CCC(OCC[N+](C)(C)C)=O)OCC[N+](C)(C)C.[Cl-].O.O.[Cl-]O=C(CCC(OCC[N+](C)(C)C)=O)OCC[N+](C)(C)C.[Cl-].O.O.[Cl-]
Molecular Weight	397,3
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2923.90
UNSPSC code	12352100

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MSDS

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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