Ectoine

Ectoine

CAT N°: 31167
Price:

From 174.00 147.90

Ectoine is a microbial metabolite that has been found in extremophilic bacteria and has photoprotectant and anti-inflammatory activities.{54497,54498} It is biosynthesized in bacteria that grow in extreme conditions, such as high temperatures, intensive sun irradiation, and drought, to protect macromolecules against environmental stressors. Ectoine (1 mM) reduces UVA-induced AP-2 activation, ICAM1 expression, and second messenger release in isolated human keratinocytes.{54497} In vivo, ectoine (100 mg/kg) reduces intestinal crypt damage, edema, and leukocyte infiltration in a mouse model of colitis induced by dextran sulfate (DSS; Item No. 23250).{54498}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (4S)-3,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid
  • Correlated keywords
    • 134522-10-4 162763-51-1 pyrostatine NSC614616 photo-protectant anitinflammatory AP2 ICAM 1
  • Product Overview:
    Ectoine is a microbial metabolite that has been found in extremophilic bacteria and has photoprotectant and anti-inflammatory activities.{54497,54498} It is biosynthesized in bacteria that grow in extreme conditions, such as high temperatures, intensive sun irradiation, and drought, to protect macromolecules against environmental stressors. Ectoine (1 mM) reduces UVA-induced AP-2 activation, ICAM1 expression, and second messenger release in isolated human keratinocytes.{54497} In vivo, ectoine (100 mg/kg) reduces intestinal crypt damage, edema, and leukocyte infiltration in a mouse model of colitis induced by dextran sulfate (DSS; Item No. 23250).{54498}

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