Atropine-d5

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Atropine-d₅

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Cat No: 30734

Biochemicals - Isotopically Labeled Standards

Atropine-d5 is intended for use as an internal standard for the quantification of atropine (Item No. 12008) by GC- or LC-MS. Atropine is a tropane alkaloid that has been found in A. belladonna and acts as a non-selective, competitive antagonist of mus...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-(phenyl-d5)propanoate

Correlated keywords:

deuterated deuterium GCMS LCMS Atropa nonselective Tropinetropate acetyl-choline

Product Overview:
Atropine-d5 is intended for use as an internal standard for the quantification of atropine (Item No. 12008) by GC- or LC-MS. Atropine is a tropane alkaloid that has been found in A. belladonna and acts as a non-selective, competitive antagonist of muscarinic acetylcholine receptors (KBs = 0.16-1.26 nM for the M1-M5 receptors).{46975,22121} Atropine increases firing of the sinoatrial node and conduction through the atrioventricular node of the heart, opposes the actions of the vagus nerve, blocks acetylcholine receptor sites, and decreases bronchial secretions.{22120} Formulations containing atropine have been used to induce mydriasis for ophthalmological exams and in the treatment of cardiac arrest and organophosphate pesticide or muscarinic mushroom poisoning.

Size	2.5 mg
Shipping	dry ice
Molecular Formula	C₁₇H₁₈D₅NO₃
SMILES	O=C(C(C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])CO)O[C@H]2C[C@@H](CC3)N(C)[C@@H]3C2
Molecular Weight	294,4
Formulation	A solid
Purity	≥99% deuterated forms (d1-d5)
Custom Code	3822.19
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.