ACE2 (human) Monoclonal Antibody

Confirm delete?

ACE2 (human) Monoclonal Antibody (Clone AC18F)

Zoom

Cat No: 30582

Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded by ACE2 in humans.{53456,53457} It is a type I transmembrane protein composed of a cytoplasmic tail and an extracellular domain containing an HEMGH motif,...

This product can only be bought through Cayman Chemical. Please contact us.

Product Overview
Data
Downloads
About Cayman

Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

ACE-2 1 SARSCoV CoV2 SARSCoV2 Anti-body AC18-F AC-18F MPROT-15

Product Overview:
Angiotensin-converting enzyme 2 (ACE2) is a carboxypeptidase and homolog of ACE1 that is encoded by ACE2 in humans.{53456,53457} It is a type I transmembrane protein composed of a cytoplasmic tail and an extracellular domain containing an HEMGH motif, characteristic of zinc-metallopeptidases, which exhibits carboxymonopeptidase activity.{53456} ACE2 is expressed in vascular endothelial cells where it catalyzes the conversion of angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to the vasodilatory peptide angiotensin 1-7 to regulate systemic blood pressure.{53456,53457} It is also expressed in the epithelial cells of the kidney, heart, lung, small intestine, and liver and has roles in fluid homeostasis, cardiac contractility, and amino acid absorption, as well as the prevention of pulmonary fibrosis and hypertension. ACE2 also acts as a functional receptor for severe acute respiratory syndrome coronavirus (SARS-CoV) and SARS-CoV-2 to facilitate viral entry into host cells.{49542,53458} Cayman's ACE2 (human) Monoclonal Antibody (Clone AC18F) can be used for ELISA, flow cytometry (FC), and Western blot (WB) applications.

Size	50 µg
Shipping	dry ice
Host	Mouse
Antigen	Recombinant human ACE2
Clone	AC18F
Isotype	IgG1?
Application(s)	ELISA, FC, and WB
Formulation	50 or 100 µg of protein G-purified monoclonal antibody
Custom Code	3822.19
UNSPSC code	12352203

Technical File

MSDS

Click here to ask for your quote and get 15% off Cayman's products.

Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.