FOX1 Monoclonal Antibody

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Cat No: 29264

FOX1, also known as ataxin-2-binding protein 1 (A2BP1) and RNA binding protein fox-1 homolog 1 (RBFOX1), is an RNA binding protein and alternative splicing regulator encoded by RBFOX1 in humans.{55207,55208,55209} RBFOX1 is expressed in the brain, ske...

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Territorial Availability: Available through Bertin Technologies only in France

Correlated keywords:

A-2BP1 A2-BP1 A2BP A2B-P FOX-1 RB Escherichia

Product Overview:
FOX1, also known as ataxin-2-binding protein 1 (A2BP1) and RNA binding protein fox-1 homolog 1 (RBFOX1), is an RNA binding protein and alternative splicing regulator encoded by RBFOX1 in humans.{55207,55208,55209} RBFOX1 is expressed in the brain, skeletal muscle, and heart and undergoes splicing to generate tissue-specific isoforms.{55215} Neuron-specific FOX1 regulates alternative splicing of genes involved in neuronal development, proliferation, and maintenance.{55207} Mutations in RBFOX1, including exon deletion, frameshift, and copy number mutations, have been found in patients with rolandic epilepsy, autism, and schizophrenia.{55208,55220,55223} Cayman's FOX1 Monoclonal Antibody can be used for immunofluorescence (IF) and Western blot (WB) applications. The antibody recognizes FOX1 isoforms at approximately 46 and 48 kDa from human, bovine, mouse, and rat samples.

Size	100 µg
Shipping	dry ice
Host	Mouse
Antigen	Recombinant protein from the N-terminus of human FOX1 expressed in E. coli
Application(s)	IF, WB
Formulation	100 µl of protein G-purified monoclonal antibody
Custom Code	3822.19
UNSPSC code	12352203

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.