Ginsenoside Rc

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Ginsenoside Rc

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Cat No: 29088

Biochemicals - Ion Channel Modulation

Ginsenoside Rc is a saponin that has been found in P. ginseng and has diverse biological activities, including antioxidant, anti-inflammatory, and nootropic properties.{45626,45627,45628} It prevents UVB-induced increases in the levels of reactive oxy...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?,12?)-20-[(6-O-?-L-arabinofuranosyl-?-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-?-D-glucopyranosyl-?-D-glucopyranoside

Correlated keywords:

52286-73-4 52590-96-2 75047-29-9 212055-72-6 Dammarane GinsenosideRc NSC310104 PanaxosideRc panax antiinflammatory oxidant Il-1b Ifnb-1 RAW264.7 LPSD ?1-?1-?2S

Product Overview:
Ginsenoside Rc is a saponin that has been found in P. ginseng and has diverse biological activities, including antioxidant, anti-inflammatory, and nootropic properties.{45626,45627,45628} It prevents UVB-induced increases in the levels of reactive oxygen species (ROS) in HaCaT keratinocytes by 34.3, 54.4, and 65.4% when used at concentrations of 5, 12, and 30 µM, respectively.{45626} Ginsenoside Rc (40 µg/ml) reduces increases in the expression of Tnf, Il1b, and Ifnb1 induced by LPS in RAW 264.7 cells.{45627} It reduces gastric ulcer and joint lesion indices in mouse models of HCl/ethanol-induced gastritis and collagen-induced arthritis, respectively, as well as reduces increased serum levels of aspartate aminotransferase (AST) induced by LPS/D-galactosamine in a mouse model of hepatitis, when administered at a dose of 20 mg/kg. Ginsenoside Rc increases GABA-induced inward current in Xenopus oocytes expressing recombinant human α1β1ɣ2S subunit-containing GABAA receptors with an EC50 value of 53.2 µM.{45628}

Size	5 mg
Shipping	dry ice
CAS Number	11021-14-0
Molecular Formula	C₅₃H₉₀O₂₂
SMILES	O[C@H]1[C@@]2([H])[C@](CC[C@]2([H])[C@@](CC/C=C(C)/C)(C)O[C@@H]3O[C@H](CO[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O4)[C@@H](O)[C@H](O)[C@H]3O)(C)[C@]5(C)CC[C@]6([H])[C@@](CC[C@H](O[C@H]7[C@H](O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)[C@@H](O)[C@H](O)[C@@H](CO)
Molecular Weight	1079,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

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Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.