trans-Zeatin-d5

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trans-Zeatin-d₅

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Cat No: 28534

Biochemicals - Isotopically Labeled Standards

trans-Zeatin-d5 is intended for use as an internal standard for the quantification of trans-zeatin (Item No. 13226) by GC- or LC-MS. trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.{48717,48718,17848,...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

2E-methyl-d3-4-(9H-purin-6-ylamino)-but-2-en-1,1-d2-1-ol

Correlated keywords:

GCMS LCMS deuterated deuterium d-5 P-735A P735-A AHK-3

Product Overview:
trans-Zeatin-d5 is intended for use as an internal standard for the quantification of trans-zeatin (Item No. 13226) by GC- or LC-MS. trans-Zeatin is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.{48717,48718,17848,48719} It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM.{17848} trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner.{48717} It increases callus growth and shoot formation in N. tabacum calluses when used at concentrations of 5 and 50 µM.{48718} trans-Zeatin (25-100 µM) reduces production of reactive oxygen species (ROS) induced by amyloid β (25-35) (Aβ25-35) in PC12 cells.{48719} It reduces scopolamine-induced spontaneous alternations in the Y-maze, indicating enhanced spatial memory, in mice when administered at doses of 1.5, 3, and 4.5 mg/kg per day.

Size	500 µg
Shipping	dry ice
Molecular Formula	C₁₀H₈D₅N₅O
SMILES	OC([2H])([2H])/C(C([2H])([2H])[2H])=C/CNC1=NC=NC2=C1N=CN2
Molecular Weight	224,3
Formulation	A solid
Purity	≥99% deuterated forms (d1-d5)
Custom Code	3822.19
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

trans-Zeatin-d₅

trans-Zeatin-d₅