Prostaglandin D2 methyl ester

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Prostaglandin D₂ methyl ester

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Cat No: 10008385

Biochemicals - Lipids

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.{416} It causes vasodilation, flushing, hypotension, and is an inhibitor o...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9?,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid, methyl ester

Correlated keywords:

esters prodrug H-PGDS synthases platelets aggregation mast cells hematopoietic allergic allergy asthmatic anaphylaxis vasodilation hypotension inhibits inhibitors inhibition brain b-trace .beta.-trace betatrace sleep prostaglandins

Product Overview:
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is produced in large quantities by hematopoietic PGD synthase during allergic and asthmatic anaphylaxis.{416} It causes vasodilation, flushing, hypotension, and is an inhibitor of platelet aggregation.{416,580} Prostaglandin D2 methyl ester (PGD2 methyl ester) is a more lipid-soluble, cell-permeable prodrug form of PGD2.{14117} It binds to the human and mouse PGD2 receptors (DP1 and CRTH2/DP2) with 5-10 fold lower affinity than PGD2.{11494}

Size	500 µg
Shipping	dry ice
CAS Number	49852-81-5
Molecular Formula	C₂₁H₃₄O₅
SMILES	CCCCCC(O)/C=C/[C@H]1C(=O)CC(O)C1C/C=C\CCCC(=O)OC
Molecular Weight	366,5
Formulation	A solution in methyl acetate
Purity	≥97%
Custom Code	2937.50
UNSPSC code	12352100

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