Glatiramer (acetate)

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Cat No: 9000571

Biochemicals - Peptides

Glatiramer (acetate) is a mixture of synthetic polypeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

L-glutamic acid, polymer with L-alanine, L-lysine, and L-tyrosine, acetate

Correlated keywords:

943513-95-9 56-41-7 56-86-0 56-87-1 60-18-4 cop-1 cop1 polyamide copaxone copolymer1 escadra Hangzhou natco polimunol probioglat protiramer TV5010 TV-5010 antiinflammatory CNS MS major histocompatibility complex 2 AA ala glu lys tyr GA

Product Overview:
Glatiramer (acetate) is a mixture of synthetic polypeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery and induces the production of immunomodulatory molecules considered to be anti-inflammatory.{33964} It also increases proliferation of oligodendrocyte and neuronal precursor cells in the central nervous system of mice.{33965,33963} Formulations containing glatiramer (acetate) are used to treat patients with multiple sclerosis, particularly the relapsing-remitting type.{33966}

Size	1 mg
Shipping	dry ice
CAS Number	147245-92-9
Molecular Formula	(C₉H₁₁NO₃ • C₆H₁₄N₂O₂ • C₅H₉
SMILES	OC(C)=O.OC1=CC=C(C[C@H](N)C(O)=O)C=C1.OC([C@@H](N)CCCCN)=O.OC(CC[C@H](N)C(O)=O)=O.OC([C@@H](N)C)=O
Molecular Weight	293,3
Formulation	A crystalline solid
Purity	≥95%
Custom Code	2918.99
UNSPSC code	12352100

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MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.