Cholesterol Uptake Cell-<wbr/>Based Assay Kit

Cholesterol Uptake Cell-Based Assay Kit

CAT N°: 600440
Price:

326.00 277.10

Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. However, the mechanisms controlling cholesterol absorption are not well understood. A better understanding of the relationship between cholesterol absorption and synthesis may allow for the development of powerful novel strategies for the prevention and treatment of hypercholesterolemia. Cayman’s Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control.

Territorial Availability: Available through Bertin Technologies only in France

  • Correlated keywords
    • assays kits measures measurements cells hormones intermediates bile acids biosynthesis body cholesterols homeostasis de novo dietary absorption biliary clearance excretion plasma hypercholesterolemia cardiovascular diseases serum hepatic Ezetimibe inhibitors inhibits inhibition intestinal uptake enterocytes proteins Niemann-Pick C1 Like 1 NPC1L1 genes influx efflux intraluminal molecules membranes modulators NBD cultured U18666A inhibitor inhibits inhibition positive controls U 18666A U-18666A
  • Product Overview:
    Maintaining body cholesterol homeostasis is critical for normal physiological functions and is achieved by a highly regulated balance of de novo synthesis, dietary cholesterol absorption, biliary clearance, and excretion. However, the mechanisms controlling cholesterol absorption are not well understood. A better understanding of the relationship between cholesterol absorption and synthesis may allow for the development of powerful novel strategies for the prevention and treatment of hypercholesterolemia. Cayman’s Cholesterol Uptake Cell-Based Assay Kit provides a convenient tool for studying cholesterol absorption modulators. The kit employs NBD Cholesterol, a fluorescently tagged cholesterol, as a probe for the detection of cholesterol taken up by cultured cells. U-18666A, a cholesterol intracellular trafficking inhibitor, is included as a positive control.

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