Palmitoyl N-Isopropylamide

Biochemicals - Lipids

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Cat No: 91354

Biochemicals - Lipids

PIA is a synthetic analog of palmitoyl ethanolamide which incorporates isopropyl amide in place of the native ethanolamide. PIA does not bind appreciably to either CB1 or CB2 receptors.{9113} PIA inhibits both the transport (re-uptake) of tritiated AE...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

N-isopropyl-hexadecanamide

Correlated keywords:

cannabinoids FAAH fatty acid amide hydrolase inhibits inhibitors inhibition ethanolamides palmitoyl-n-isopropylamide PEA neurochemistry neuroscience synthetic analogs hydrolysis ethanolamines

Product Overview:
PIA is a synthetic analog of palmitoyl ethanolamide which incorporates isopropyl amide in place of the native ethanolamide. PIA does not bind appreciably to either CB1 or CB2 receptors.{9113} PIA inhibits both the transport (re-uptake) of tritiated AEA into intact cells, as well as the subsequent hydrolysis of AEA to arachidonate and ethanolamine, with 50% inhibition of FAAH-mediated hydrolysis at 10 µM.{9113}

Size	5 mg
Shipping	dry ice
CAS Number	189939-61-5
Molecular Formula	C₁₉H₃₉NO
SMILES	CCCCCCCCCCCCCCCC(=O)NC(C)C
Molecular Weight	297,5
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2915.90
UNSPSC code	12352100

Technical File

MSDS

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.

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