Sulfapyridine

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Sulfapyridine

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Cat No: 28619

Sulfapyridine is a sulfonamide antibiotic with antibacterial and anti-inflammatory activities.{45549} It is also a metabolite of sulfasalazine (Item No. 15025) formed through bacterial conversion in the colon.{45550} It is active against strains of Y....

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

4-amino-N-2-pyridinyl-benzenesulfonamide

Correlated keywords:

Ro 1-4303 Ro14303 Ro1 14303 M&B 693 M&B693 MB MB693 A-499 A499 Adiplon Coccoclase Dagenan Eubasin Eubasinum Haptocil N1-2-Pyridylsulfanilamide NSC4753 NSC41791 Piridazol Pirodazole Plurazol Pyriamid Pyridazol Relbapiridina Ronin Septipulmon Streptosilpyridine Sulfanilamide Sulfidin Sulfidine Thioseptal Trianon

Product Overview:
Sulfapyridine is a sulfonamide antibiotic with antibacterial and anti-inflammatory activities.{45549} It is also a metabolite of sulfasalazine (Item No. 15025) formed through bacterial conversion in the colon.{45550} It is active against strains of Y. enterocolitica and Salmonella (MICs = 3.1-25 and 25-100 μg/ml, respectively), as well as S. aureus (MBC = 0.8 μM).{45551,45552} It is an inhibitor of recombinant P. carinii dihydropteroate synthetase (DHPS; IC50 = 0.18 μM).{38582} Sulfapyridine scavenges peroxyl radicals in an oxygen radical absorbance capacity (ORAC) assay.{45550} It inhibits histamine release induced by compound 48/80 (Item No. 22173) from isolated rat peritoneal mast cells in a dose-dependent manner.{45553} Sulfapyridine (1 μg/kg) also inhibits compound 48/80-induced systemic allergic reaction in rats. Formulations containing sulfapyridine have previously been used in the treatment of dermatological conditions and ulcerative colitis.

Size	5 g
Shipping	dry ice
CAS Number	144-83-2
Molecular Formula	C₁₁H₁₁N₃O₂S
SMILES	NC1=CC=C(S(NC2=CC=CC=N2)(=O)=O)C=C1
Molecular Weight	249,3
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2935.90
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.