Nicotinamide N-oxide

Nicotinamide N-oxide

CAT N°: 28441
Price:

From 66.00 56.10

Nicotinamide N-oxide is a metabolite of nicotinamide (Item No. 11127).{47708} It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; Item No. 17341), indicating cell differentiation, in HL-60 promyelocytic leukemia cells.{47709} Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.{47710}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 3-pyridinecarboxamide, 1-oxide
  • Correlated keywords
    • Niacinamide NSC30531 NSC168416 P 450 CYP 2E1 HL60
  • Product Overview:
    Nicotinamide N-oxide is a metabolite of nicotinamide (Item No. 11127).{47708} It is formed via oxidation of nicotinamide by the cytochrome P450 (CYP) isoform CYP2E1. Nicotinamide N-oxide (30 mM) inhibits proliferation and induces reduction of nitroblue tetrazolium (NBT; Item No. 17341), indicating cell differentiation, in HL-60 promyelocytic leukemia cells.{47709} Urine levels of nicotinamide N-oxide are elevated in a mouse model of high-fat diet-induced obesity.{47710}

We also advise you