Histone H4R3Me2s (1-21)-GGK-<wbr/>biotin (trifluoro<wbr/>acetate salt)

Histone H4R3Me2s (1-21)-GGK-biotin (trifluoroacetate salt)

CAT N°: 28192
Price:

414.00 351.90

Histone H4R3Me2s (1-21)-GGK-biotin is a peptide fragment of histone H4 that corresponds to amino acid residues 2-22 of the human H4 sequence. It is symmetrically dimethylated at arginine 3 and biotinylated via a C-terminal GGK linker. Symmetric dimethylation of histone 4 at arginine 3 is associated with transcriptional repression.{45290} It can recruit the DNA methyltransferase DNMT3a, leading to DNA methylation and further transcriptional repression. Histone H4R3Me2s (1-21)-GGK-biotin has been used as a substrate for the qualitative measurement of jumonji domain containing 1B (JMJD1B) arginine demethylase activity and in dot blot assays to verify antibody specificity.{45291}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N2-(N2-acetyl-L-serylglycyl-N?,N?’-dimethyl-L-arginylglycyl-L-lysylglycylglycyl-L-lysylglycyl-L-leucylglycyl-L-lysylglycylglycyl-L-alanyl-L-lysyl-L-arginyl-L-histidyl-L-arginyl-L-lysyl-L-valylglycylglycyl)-N6-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoyl)-L-lysine, trifluoroacetate salt
  • Correlated keywords
    • Ac-Ser-Gly-Arg(Me2s)-Gly-Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala-Lys-Arg-His-Arg-Lys-Val-Gly-Gly-Lys(Biotin)-OH H-4-R3-Me-2s 4R3Me2s R3Me2s 3Me2s Me2s H4R3Me2 H4R3Me H4R3 H4R (1-21)GGK DNMT-3a 3-a DNMT3 1-B JMJD-1B JMJD1 JM JD anti-body
  • Product Overview:
    Histone H4R3Me2s (1-21)-GGK-biotin is a peptide fragment of histone H4 that corresponds to amino acid residues 2-22 of the human H4 sequence. It is symmetrically dimethylated at arginine 3 and biotinylated via a C-terminal GGK linker. Symmetric dimethylation of histone 4 at arginine 3 is associated with transcriptional repression.{45290} It can recruit the DNA methyltransferase DNMT3a, leading to DNA methylation and further transcriptional repression. Histone H4R3Me2s (1-21)-GGK-biotin has been used as a substrate for the qualitative measurement of jumonji domain containing 1B (JMJD1B) arginine demethylase activity and in dot blot assays to verify antibody specificity.{45291}

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