Histone H3K79Me1 (69-89) amide (

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Histone H3K79Me1 (69-89) amide (human, mouse, rat, bovine) (trifluoroacetate salt)

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Cat No: 28147

Biochemicals - Peptides

Histone H3K79Me1 (69-89) amide is a peptide fragment of histone H3 that corresponds to amino acid residues 70-90 of the human histone H3.1 and H3.2 sequences. Methylation of lysine 79 on histone H3 is associated with active chromatin and the silencing...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

L-arginyl-L-leucyl-L-valyl-L-arginyl-L-glutamyl-L-isoleucyl-L-alanyl-L-glutaminyl-L-?-aspartyl-L-phenylalanyl-N6-methyl-L-lysyl-L-threonyl-L-?-aspartyl-L-leucyl-L-arginyl-L-phenylalanyl-L-glutaminyl-L-seryl-L-seryl-L-alanyl-L-valinamide, trifluoroacetate salt

Correlated keywords:

H-Arg-Leu-Val-Arg-Glu-Ile-Ala-Gln-Asp-Phe-Lys(Me1)-Thr-Asp-Leu-Arg-Phe-Gln-Ser-Ser-Ala-Val-NH2 H3K79-Me1 K79Me1 K79 Me2/3 Me-2/3 H3K79Me2/3 3.1 3.2 Hoxa-9

Product Overview:
Histone H3K79Me1 (69-89) amide is a peptide fragment of histone H3 that corresponds to amino acid residues 70-90 of the human histone H3.1 and H3.2 sequences. Methylation of lysine 79 on histone H3 is associated with active chromatin and the silencing of telomere-associated genes by silent information regulator (Sir) proteins.{17798} The conversion of H3K79Me1 to H3K79Me2/3 is associated with increased expression of mixed lineage leukemia (MLL) target genes, including Hoxa9.{51045}

Size	250 µg
Shipping	dry ice
Molecular Formula	C₁₁₀H₁₈₂N₃₄O₃₂ • XCF₃COOH
SMILES	O=C(O)C(F)(F)F.NC([C@H](C(C)C)NC([C@@H](NC([C@H](CO)NC([C@H](CO)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](NC([C@@]([C@@H](C)O)([H])NC([C@H](CCCCNC)NC([C@@H](NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](NC([C@@]([C@H](CC)C)([H])NC(
Molecular Weight	2492,9
Formulation	A solid
Purity	≥95%
Custom Code	3504.00
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

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ISO/IEC 17025:2005
ISO Guide 34:2009

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