Pinoresinol Diglucoside

Pinoresinol Diglucoside

CAT N°: 27708
Price:

From 102.00 86.70

Pinoresinol diglucoside is a lignan that has been found in E. ulmoides and has diverse biological activities.{51136,51137,51138} It inhibits peroxidation of a linoleic acid emulsion by 64.2% when used at a concentration of 20 ?g/ml, scavenges hydrogen peroxide and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805), ABTS (Item No. 27317), and superoxide anion free radicals, and has ferrous ion metal chelating activity in cell-free assays.{51136} In vivo, pinoresinol diglucoside (10, 20, and 40 mg/kg) inhibits increases in serum levels of inorganic phosphate, IL-6, and TNF-? and decreases in serum calcium levels and transverse diameter, weight, bone mineral content, and bone mineral density of the right femur in a rat model of osteoporosis induced by dexamethasone (Item No. 11015).{51138}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • [(1S,3aR,4S,6aR)-tetrahydro-1H,3H-furo[3,4-c]furan-1,4-diyl]bis(2-methoxy-4,1-phenylene) bis-?-D-glucopyranoside
  • Correlated keywords
    • IL6 TNF? interleukin
  • Product Overview:
    Pinoresinol diglucoside is a lignan that has been found in E. ulmoides and has diverse biological activities.{51136,51137,51138} It inhibits peroxidation of a linoleic acid emulsion by 64.2% when used at a concentration of 20 ?g/ml, scavenges hydrogen peroxide and 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805), ABTS (Item No. 27317), and superoxide anion free radicals, and has ferrous ion metal chelating activity in cell-free assays.{51136} In vivo, pinoresinol diglucoside (10, 20, and 40 mg/kg) inhibits increases in serum levels of inorganic phosphate, IL-6, and TNF-? and decreases in serum calcium levels and transverse diameter, weight, bone mineral content, and bone mineral density of the right femur in a rat model of osteoporosis induced by dexamethasone (Item No. 11015).{51138}

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