Hederoside D2

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Hederoside D₂

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Cat No: 27507

Biochemicals - Natural Products

Hederoside D2 is a triterpenoid saponin originally isolated from C. robustum rhizome and roots and has diverse biological activities.{48429,48430} It induces potassium release and hemolysis in mouse erythrocytes in a pH-dependent manner when used at a...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

(3?,4?)-3-[(2-O-?-D-glucopyranosyl-?-L-arabinopyranosyl)oxy]-23-hydroxy-olean-12-en-28-oic acid

Correlated keywords:

12672-44-5 52038-09-2 128192-16-5 345975-32-8 D 2 1 Caulophyllum N1E115 N 1E 1E115 Akebia Std Calthoside ?-Fatsin Akeboside

Product Overview:
Hederoside D2 is a triterpenoid saponin originally isolated from C. robustum rhizome and roots and has diverse biological activities.{48429,48430} It induces potassium release and hemolysis in mouse erythrocytes in a pH-dependent manner when used at a concentration of 10 μg/ml.{48430} Hederoside D2 is cytotoxic to N1E-115 neuroblastoma cells at low pH. It induces proliferation of human embryonic fibroblasts in acidic medium, an effect that can be blocked by the calcium channel blockers verapamil (Item No. 14288), diltiazem, and nitrendipine (Item No. 17549).

Size	1 mg
Shipping	dry ice
CAS Number	20853-58-1
Molecular Formula	C₄₁H₆₆O₁₃
SMILES	CC1(C)CC[C@@](CC[C@]2(C)C3=CC[C@@]4([H])[C@@]2(C)CC[C@]5([H])[C@]4(C)CC[C@H](O[C@]6([H])OC[C@H](O)[C@H](O)[C@H]6O[C@@]7([H])[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O7)[C@@]5(C)CO)(C(O)=O)[C@@]3([H])C1
Molecular Weight	767
Formulation	A crystalline solid
Purity	≥98%
Custom Code	2932.99
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.