Ac-VEID-CHO (trifluoro<wbr/>acetate salt)

Ac-VEID-CHO (trifluoroacetate salt)

CAT N°: 27437
Price:

231.00 196.35

Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM).{43790} It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 ?M) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells.{43791} It also inhibits caspase-6-like activity in Norway spruce cell extracts when used at a concentration of 2 ?M, as well as in staurosporine-treated SKNAS neuroblastoma cells with an IC50 value of 0.49 ?M.{43790,43792}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • (4S,7S,10S,13S)-10-((S)-sec-butyl)-7-(2-carboxyethyl)-13-formyl-4-isopropyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid, trifluoroacetate salt
  • Correlated keywords
    • 319494-39-8 U-937 caspase3 caspase6
  • Product Overview:
    Ac-VEID-CHO is an inhibitor of caspase-6 (IC50 = 16.2 nM).{43790} It is selective for caspase-6 over caspase-7 (IC50 = 162.1 nM) but can also inhibit caspase-3 (IC50 = 13.6 nM). Ac-VEID-CHO (100 ?M) inhibits ricin-induced caspase-6-, but not caspase-3-, like activity in U937 cells.{43791} It also inhibits caspase-6-like activity in Norway spruce cell extracts when used at a concentration of 2 ?M, as well as in staurosporine-treated SKNAS neuroblastoma cells with an IC50 value of 0.49 ?M.{43790,43792}

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