1-Oleoyl Glycerol

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1-Oleoyl Glycerol

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Cat No: 26793

Biochemicals - Lipids

1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor ...

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Territorial Availability: Available through Bertin Technologies only in France

Synonyms:

9Z-octadecenoic acid, 2,3-dihydroxypropyl ester

Correlated keywords:

925-14-4 30836-40-9 33978-07-3 glyceryl oleate monooleoyl Monooleoylglycerol Oleoylglycerol Oleylglycerol Danisco MO 90 MO90 GO 991 GO991 monooleate sn1 mono-acylglycerol acyl MG MG(18:1(9Z)/0:0/0:0)[rac]

Product Overview:
1-Oleoyl glycerol is a monoacylglycerol containing oleic acid (Item No. 90260) at the sn-1 position. 1-Oleoyl glycerol (10%), in a formulation with cyclosporin A (Item No. 12088) in propylene glycol, enhances diffusion of cyclosporin A from the donor compartment of a Franz diffusion cell into the stratum corneum, epidermis, and dermis of porcine ear skin, as well as through the skin to the receptor compartment.{48157} Mixed micellar systems containing 1-oleoyl glycerol and bile salts increase the apparent permeability coefficient (Papp) and absorption rate of amphotericin B (Item No. 11636) in perfused rat intestine in vivo.{48158} Formulations containing 1-oleoyl glycerol have been used as emulsifying agents, food additives, and absorption enhancers.

Size	250 mg
Shipping	dry ice
CAS Number	111-03-5
Molecular Formula	C₂₁H₄₀O₄
SMILES	O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
Molecular Weight	356,5
Formulation	A solid
Purity	≥95%
Custom Code	2916.15
UNSPSC code	12352100

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Cayman Chemical's mission is to help make research possible by supplying scientists worldwide with the basic research tools necessary for advancing human and animal health. Our utmost commitment to healthcare researchers is to offer the highest quality products with an affordable pricing policy.

Our scientists are experts in the synthesis, purification, and characterization of biochemicals ranging from small drug-like heterocycles to complex biolipids, fatty acids, and many others. We are also highly skilled in all aspects of assay and antibody development, protein expression, crystallization, and structure determination.

Over the past thirty years, Cayman developed a deep knowledge base in lipid biochemistry, including research involving the arachidonic acid cascade, inositol phosphates, and cannabinoids. This knowledge enabled the production of reagents of exceptional quality for cancer, oxidative injury, epigenetics, neuroscience, inflammation, metabolism, and many additional lines of research.

Our organic and analytical chemists specialize in the rapid development of manufacturing processes and analytical methods to carry out clinical and commercial GMP-API production. Pre-clinical drug discovery efforts are currently underway in the areas of bone restoration and repair, muscular dystrophy, oncology, and inflammation. A separate group of Ph.D.-level scientists are dedicated to offering Hit-to-Lead Discovery and Profiling Services for epigenetic targets. Our knowledgeable chemists can be contracted to perform complete sample analysis for analytes measured by the majority of our assays. We also offer a wide range of analytical services using LC-MS/MS, HPLC, GC, and many other techniques.

Accreditations
ISO/IEC 17025:2005
ISO Guide 34:2009

Cayman is a leader in the field of emerging drugs of abuse, providing high-purity Schedule I-V Controlled Substances to federally-licensed laboratories and qualified academic research institutions for forensic analyses. We are certified by ACLASS Accreditation Services with dual accreditation to ISO/IEC 17025:2005 and ISO Guide 34:2009.