CAY10726

CAY10726

CAT N°: 23859
Price:

From 48.00 40.80

CAY10726 is an arylurea fatty acid.{40512} It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 ?M. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 16-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-hexadecanoic acid
  • Correlated keywords
    • CAY-10726 phosphatidyl-glycerol MDAMB231
  • Product Overview:
    CAY10726 is an arylurea fatty acid.{40512} It decreases ATP production by 28% in MDA-MB-231 breast cancer cells when used at a concentration of 10 ?M. CAY10726 decreases proliferation and initiates apoptosis in MDA-MB-231 cells via depletion of the phospholipid cardiolipin and its precursor phosphatidylglycerol from the mitochondrial membrane. In vivo, CAY10726 (2.5-40 mg/kg) reduces tumor volume and increases tumor cell apoptosis in a mouse MDA-MB-231 breast cancer xenograft model in a dose-dependent manner.

We also advise you