p,p‘-DDT

Territorial Availability: Available through Bertin Technologies only in France

• Synonyms
  • 1,1′-(2,2,2-trichloroethylidene)bis[4-chloro-benzene]
• Correlated keywords
  • 1081843-15-3 Agritan Aavero-extra Arkotine Azotox M Benzochloryl Bosan supra Bovidermol Chlorophenothane Chlorphenotoxum Chlorphenotoxum Clofenotan Deoval Detoxan Dichlorodiphenyltrichloroethane Dicophane Dodat Dykol ENT-1506 ENT1506 Estonate Ethane Gesafid FWJ Gesapon Gesarex Gesarol Guesapon Hildit Ivoran Mutoxan NSC8939 Neocid Neocidol PEB1 PEB-1 Parachlorocidum Pentachlorin Penticidum Tafidex Zerdane Anopheles Aedes Carassius DLD-1 Citox Dibovin
• Product Overview:
  p,p’-DDT is an organochlorine pesticide that induces 94.2% mortality of malaria mosquito (A. quadrimaculatus) fourth-instar larvae and 100% mortality of A. aegypti larvae when used at concentrations of 0.01 and 0.05 ppm, respectively.{37594,37593} It increases secretion of estradiol by granulosa and theca cell co-cultures isolated from porcine ovarian follicles when used at concentrations of greater than or equal to 4 ng/ml and increases apoptosis in isolated human peripheral blood mononuclear cells (PBMCs) when used at concentrations ranging from 80 to 150 µg/ml.{36699,39802} p,p’-DDT (5 nmol/kg, i.p.) increases tumor growth in a DLD1 colorectal adenocarcinoma nude mouse xenograft model.{43286} It induces 100% mortality of C. auratus (goldfish) at 0.25 ppm and is lethal to rats but not hamsters (LD50s = 120 and ~5,000 mg/kg, respectively).{36700,37594} p,p’-DDT is a persistent organic pollutant (POP) and is elevated in the sera of pregnant women in malaria-endemic regions of South Africa.{37597} Formulations containing p,p’-DDT have been used to control insect populations, including mosquitos, in agriculture and to prevent the spread of malaria and typhus.