Porcupine-IN-1

Porcupine-IN-1

CAT N°: 25834
Price:

From 146.00 124.10

Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays).{47087,47088} It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 ?M, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.{47087}

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • N-[(3-fluoro-2′-methyl[2,4′-bipyridin]-5-yl)methyl]-9H-carbazole-2-carboxamide
  • Correlated keywords
    • PORCN-IN-1 IN1 3A HEK 293T PORCNIN1
  • Product Overview:
    Porcupine-IN-1 is an inhibitor of the Wnt and hedgehog signaling pathways (IC50s = 0.5 and 71 nM, respectively, in cell-based reporter assays).{47087,47088} It inhibits secretion of Wnt3A from Wnt3A-transfected HEK293T cells when used at a concentration of 0.1 ?M, indicating inhibition of porcupine, an enzyme that catalyzes palmitoylation of Wnt proteins.{47087}

We also advise you