Pipequaline

Pipequaline

CAT N°: 23888
Price:

From 122.00 103.70

Pipequaline is a partial agonist of central benzodiazepine receptors (Ki = 78 nM in a radioligand binding assay).{35203} In mice, pipequaline enhances the effects of diazepam (Item No. ISO60177), further reducing foot shock-induced fighting behavior and the number of maximal electroshock-induced seizures and potentiating the muscle relaxant and hypnotic effects.{39426} Pipequaline also increases drinking in the Vogel punished drinking task indicating anxiolytic-like activity that can be reversed by the benzodiazepine receptor antagonist flumazenil (Item No. 14252).

Territorial Availability: Available through Bertin Technologies only in France

  • Synonyms
    • 2-phenyl-4-[2-(4-piperidinyl)ethyl]-quinoline
  • Correlated keywords
    • 45319RP PK8165
  • Product Overview:
    Pipequaline is a partial agonist of central benzodiazepine receptors (Ki = 78 nM in a radioligand binding assay).{35203} In mice, pipequaline enhances the effects of diazepam (Item No. ISO60177), further reducing foot shock-induced fighting behavior and the number of maximal electroshock-induced seizures and potentiating the muscle relaxant and hypnotic effects.{39426} Pipequaline also increases drinking in the Vogel punished drinking task indicating anxiolytic-like activity that can be reversed by the benzodiazepine receptor antagonist flumazenil (Item No. 14252).

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