PI3-<wbr/>Kinase ? Inhibitor 2

PI3-Kinase ? Inhibitor 2

CAT N°: 10010177
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From 42.00 35.70

PI3-Kinase ? (PI3K?) inhibitor 2 is an inhibitor of PI3K p110? (IC50 = 2 nM in an enzyme assay).{14907} It is selective for p110? over p110?, p110?, and PI3K C2? (IC50s = 16, 660, and 220 nM, respectively). It also inhibits mammalian target of rapamycin (mTOR; IC50 = 49 nM).{42914} PI3K? inhibitor 2 inhibits proliferation in A375 melanoma cells with an IC50 value of 0.58 ?M.{14907}

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