Phenylarsine Oxide

Phenylarsine Oxide

CAT N°: 35525
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From 43.00 36.55

Phenylarsine oxide is an organoarsenic compound.{68019} It inhibits insulin-induced protein phosphatase 1 (PP1) activity and glucose transporter 4 (Glut4) translocation in rat adipocytes when used at a concentration of 5 µM. Phenylarsine oxide completely inhibits insulin-induced PI3K activation and glucose transport in 3T3-L1 adipocytes when used at concentrations of 30 and 50 µM, respectively.{68023} It inhibits potassium chloride-induced exocytosis and induces mitochondrial depolarization in isolated rat brain synaptosomes.{68024} Phenylarsine oxide (0.3 and 1 mg/kg, i.p.) reduces LPS-induced neutrophil infiltration in bronchoalveolar lavage fluid (BALF) and carrageenan-induced paw edema in rats.{68025}

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